Dr. Baum is the CEO at Terremoto and has served on the board of directors since July 2023. Prior to becoming the CEO at Terremoto, Chuck was the Founder, President and Chief Executive Officer of Mirati Therapeutics, where he also served as a Board Member since 2012 through its recent acquisition by Bristol Meyers Squibb in 2024. He was Founder, President and Head of Research and Development at Mirati from 2021 to 2023 and was President, Founder and CEO from Nov 2012 to 2021.
Under his leadership, Mirati transformed into a precision oncology company focused on advancing drug discovery and research and delivering novel therapeutics that target the genetic drivers of cancer. Mirati discovered, developed and commercialized Krazati* (adagrasib) for the treatment of NSCLC patients with KRAS G12C mutations. Mirati also discovered a number of other novel, first in class or best in class inhibitors that target KRAS G12D, PRMT5, SOS1 and other critical oncology pathways.
Prior to his tenure at Mirati, Dr. Baum held positions of increasing responsibility in research and development at Pfizer from 2003 to 2012, where he was responsible for the development of several major drugs, including Inlyta®, Xalkori®, Ibrance® and Sutent®. While at Schering Plough he contributed to the development of Temodar® for the treatment of patients with glioblastoma.
Chuck’s career has also included academic and hospital positions at Stanford and Emory universities. He currently serves on the board of directors at Poseida Therapeutics, PMV Pharma, Acrivon Therapeutics, Odyssey Therapeutics and Crossbow Therapeutics. Chuck is also on the Scientific Advisory Board at ALX Oncology. Previously, he served as a member of the board of Array Biopharma from 2014 to 2019 when it was acquired by Pfizer, Inc., Immunomedics from 2019 to 2020 when it was acquired by Gilead, and BCTG Acquisition Corp from 2020 to 2021 when it merged with Tango Therapeutics.
Chuck received his M.D. and Ph.D. degrees from Washington University School of Medicine and completed his post-graduate training at Stanford University. Additionally, he has received research support from the National Institutes of Health and the American Cancer Society, published more than 50 peer-reviewed manuscripts and holds a number of patents and patent applications.