Senior Accountant

ALX Oncology is a publicly traded, clinical-stage immuno-oncology company focused on helping patients fight cancer by developing therapies that block the CD47 checkpoint pathway. Our lead candidate, ALX148, is a next generation CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated proprietary Fc domain. ALX148 has demonstrated promising clinical responses across a range of hematologic and solid malignancies in combination with a number of leading anti-cancer agents.

The individual will provide accounting and finance expertise to support the business strategy for the company’s growing oncology portfolio. This position will initially report to the Accounting Manager and will be located in South San Francisco, CA.


These may include but are not limited to: 

  • Ensures accuracy of financial transactions and ensures processes align with company accounting policies/procedures.
  • Ensures timely and accurate month-end, quarter-end, and year-end closing in accordance with GAAP.
  • Ability to maintain the general ledger of the parent company and foreign subsidiaries.
  • Preparation of journal entries and reconciliations for areas such as cash and investments, fixed assets, prepaids, payroll, and various accruals. 
  • Assist during the monthly close process on other areas such as clinical and CMC accruals.
  • Assist with SOX 404(b) testing and SEC reporting, as needed.
  • Responsible for the preparation of schedules for the external audit related to their areas of responsibility and working directly with the audit team to resolve any questions they may have on these areas.
  • Responsible for the preparation of the annual 1099 forms for our vendors as well as other areas of tax compliance such as property and use taxes.
  • Responsible for processing payroll twice monthly and resolving any payroll-related issues that may arise.
  • Assist reviewing AP invoices for proper coding, signing authority, and accuracy.
  • Assist reviewing new vendors and purchase orders.
  • Perform other duties as assigned or required.
  • Support the organization in maintaining a work environment focused on quality and that fosters learning, open communication, collaboration, integration and teamwork.


  • Bachelor’s degree in Accounting/Finance or related study.
  • 2+ years of public accounting experience or 5+ year of related work experience.
  • CPA preferred but not required.
  • Big 4 experience preferred but not required.
  • Strong understanding of US GAAP, financial reporting, and internal controls.
  • Experience with SEC Regulations and SOX compliance.
  • Experience in the life sciences, biotechnology or pharmaceutical industry highly desired.
  • Must possess the ability to multi-task and work in time sensitive situations to meet deadlines despite distractions and changing priorities.
  • High level of attention to detail, aptitude for planning/managing deadlines.
  • Must possess excellent interpersonal, communication (oral and written), organizational, and project planning skills.
  • Must have ability to effectively work and communicate with all levels of employees throughout the company. Should be customer service driven and have positive outlook.
  • Previous experience with mid-sized ERP systems, preferably NetSuite, and other accounting software.
  • Computer literacy required, with the ability to navigate computer systems with little or no assistance.  Proficiency in MS Office and Outlook software specifically experience with Word, Excel and PowerPoint.
  • Ability to self-motivate and function independently, driven towards superior effort and performance, and the desire to work in a very dynamic environment.

ALX Oncology is an equal opportunity employer. All applicants should be legally entitled to work for any employer in the US. Title and salary are commensurate with experience. Our compensation program includes competitive salary, equity participation and attractive bonus incentives.

To apply for this position, please send your cover letter and resume to